Leukocyte Telomere Length in Postmenopausal Women
نویسندگان
چکیده
منابع مشابه
A Prospective Study of Leukocyte Telomere Length and Risk of Type 2 Diabetes in Postmenopausal Women
Telomere length (TL) has been implicated in the pathogenesis of age-related disorders. However, there are no prospective studies directly investigating the role of TL and relevant genes in diabetes development. In the multiethnic Women's Health Initiative, we identified 1,675 incident diabetes case participants in 6 years of follow-up and 2,382 control participants matched by age, ethnicity, cl...
متن کاملDietary restraint and telomere length in pre- and postmenopausal women.
BACKGROUND Leukocyte telomere shortening can serve as a biomarker of aging, as telomere length (TL) can decline with age and shortening is positively associated with morbidity and mortality. It is therefore important to identify psychological and behavioral factors linked to accelerated telomere shortening. Stress and poorer metabolic health (greater adiposity, insulin resistance, and cortisol)...
متن کاملHealthy Lifestyle and Leukocyte Telomere Length in U.S. Women
CONTEXT Whether a healthy lifestyle may be associated with longer telomere length is largely unknown. OBJECTIVES To examine healthy lifestyle practices, which are primary prevention measures against major age-related chronic diseases, in relation to leukocyte telomere length. DESIGN AND SETTING Cross-sectional analysis in the Nurses' Health Study (NHS). PARTICIPANTS The population consist...
متن کاملLeukocyte telomere length: the telomere tale continues.
In culture, replicating human somatic cells display progressive telomere shortening. Ultimately, such cells either undergo apoptosis or enter a state of replicative senescence that is triggered by critically shortened telomeres. Accordingly, telomere length is an index of both the replicative history and the replicative potential of human somatic cells in culture (1). Most replicating human som...
متن کاملIndependent and Combined Effects of Dietary Weight Loss and Exercise on Leukocyte Telomere Length in Postmenopausal Women
OBJECTIVE Investigate the effects of 12 months of dietary weight loss and/or aerobic exercise on leukocyte telomere length in postmenopausal women. DESIGN AND METHODS Four hundred and thirty nine overweight or obese women (50-75 years) were randomized to: (i) dietary weight loss (N = 118); (ii) aerobic exercise (N = 117), (iii) diet + exercise (N = 117), or (iv) control (N = 87). The diet int...
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ژورنال
عنوان ژورنال: Journal of Obstetric, Gynecologic & Neonatal Nursing
سال: 2017
ISSN: 0884-2175
DOI: 10.1016/j.jogn.2017.03.006